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For human samples, plasma collected at baseline (fasting) and at 30 and 120 minutes after the mixed meal or plasma collected at baseline (fasting) and at 40 and 100 minutes after initiation of the hyperinsulinemic-hypoglycemic clamp was assayed by serotonin ELISA (ADI-900-175, Enzo) following the manufacturers instructions

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Beyond glycemic effects, GLP-1 receptor agonists slow gastric emptying, which prolongs the sensation of fullness after meals and contributes to reduced caloric intake

doi: 10.3389/fimmu.2023.1148209 107