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To enhance the effectiveness of therapies, it may be imperative to employ tactics such as regulating tumor vasculature, augmenting vascular permeability, or facilitating access through the BBB

We therefore examined the protein expression of FOXO3a and p-FOXO3a in the in vitro model

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Additionally, some studies have shown that volanesorsen, an antisense oligonucleotide that inhibits ApoC-III mRNA translation, can reduce ApoC-III levels by up to 70% in healthy individuals and 80% in patients with hyperglycemia 119,120