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Calcium-mobilization and Gq/PLC signaling assays
Burak Altintas, MD, an orthopedist with UTMB, who was not involved in this study, further highlighted the following limitations of the research: The limitations include retrospective design and likely residual confounding despite matching as fracture risk is influenced by many variables that are not reported [] Further, the comparison group is heterogeneous, combining another GLP-1 receptor agonist (dulaglutide) with two mechanistically different weight-loss medications
Fernandes, L
We further examined the protein expression and activation states of Smad2 and Smad3, which are downstream effectors of TGF signaling, in NP cells treated with L929 conditioned media
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