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Mylan, for example, has utilized a combination of SPPS and Liquid-Phase Peptide Synthesis (LPPS) to increase yields and reduce costs for liraglutide

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However, in a low Her2-expressing cell line, lower Her2 binding variant (Her2mA-CD3) did not show a significant cell killing at the 0.1 nM when co-cultured with T cells while the parental and Her2mB-CD3 selectively demonstrated significant cell killing at the same concentration