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Conclusions Our study found no significant difference in the incidence of overcorrection between proactive and reactive DDAVP strategies, in conjunction with 3%NaCl, for treating severe symptomatic hyponatremia

Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig