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Metabolic Conditions Homocystinuria : A metabolic disorder characterized by an accumulation of homocysteine due to MTHFR enzyme dysfunction

The most commonly reported side effect among those who took orforglipron included mild to moderate gastrointestinal issues, such as constipation, diarrhea, indigestion, nausea, and vomiting

Theres ongoing research around their benefit for a host of other conditions including dementia drug and alcohol addiction