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In some aspects, the invention provides methods of treating dementia patients at various stages of dementia, and/or of slowing and/or preventing the progression of dementia to later stages of dementia, or even or reversing the "staging" from advanced to moderate or early, or from moderate to early, stage

300,301 This not only affects the intracellular signaling of macrophages but also their response to the external environment, including their effects on chondrocytes and other synovial cells

10.2165/00003495-200161140-00003 [DOI] [PubMed] [Google Scholar] Sanchez-Marzo N., Perez-Sanchez A., Ruiz-Torres V., Martinez-Tebar A., Castillo J., Herranz-Lopez M., et al

In this step, the microspheres are suspended in the same continuous-phase processing medium used in step one, with or without surfactant, or in another liquid