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Wegovy is a GLP-1 receptor agonist (RA) drug primarily used for weight management through appetite suppression

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reported that the apparent permeability coefficient (Papp) of the pegylated formulation was 3.04 10 4 cm min 1 , significantly higher than that of plain liposomes (2.17 10 4 cm min 1 ) and drug suspensions (0.9 10 4 cm min 1 ), indicating that PEG facilitates liposome penetration through the mucus layer and promotes transintestinal wall transport

Kamierczak Z, Szostak-Paluch K, Przybyo M, Langner M, Witkiewicz W, Jdruchniewicz N et al (2020) Endocytosis in cellular uptake of drug delivery vectors, Molecular aspects in drug development