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Adewunmi, O., Shen, Y., Zhang, X

Interestingly, the increases in MEK1/2 and p70S6K1 phosphorylation were also observed when cells were subjected to the treatment of AKT inhibitor or genetic knockdown of AKT2 but not AKT1, suggesting that AKT2 inhibition stimulates MEK1/2 phosphorylation to activate p70S6K1

Rodriguez-Diaz R, Dando R, Huang YA, Berggren P-O, Roper SD, Caicedo A (2012) Real-time detection of acetylcholine release from the human endocrine pancreas