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For patients experiencing significant heartburn on tirzepatide or who carry genetic variations affecting peptide sensitivity, PlexusDx offers the Precision Peptide Genetic Test ($99 after your first month of treatment)

For patients seeking additional precision, the PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month of treatment) maps 14 pathways, 49 peptides, and 150+ genetic insights related to GLP-1 and GIP receptor function, appetite regulation, and metabolic factors

The p53 protein, a key human tumor suppressor, regulates the expression of oncogenes and downstream signaling pathways, contributing to biological effects (7275): Beyond its role in cancer, p53 is highly expressed in the brain, where it influences dendritic growth, oxidative stress response, apoptosis and autophagy, making p53 dysfunction and associated pathways noteworthy in the pathogenesis of AD (7678)