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Contemporary research applications span diverse fields including aging biology, tissue regeneration, cancer research, and regenerative medicine, with laboratory models demonstrating remarkable restoration of tissue homeostasis in both accelerated and natural aging conditions
Finally, the absence of validated biomarkers for predicting treatment response or monitoring efficacy further complicates both clinical research and practical application, limiting the ability to personalize therapy or objectively assess outcomes
As inflammation decreases, melanogenesis signalling may also reduce
J Immunol Baltim Md 212:5768
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