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The iron-loaded transferrin is then recognized by the cell membrane receptor TfR1 and translocated into endosomes via the receptor-mediated endocytosis pathway, where ferric ions are released from the transferrin in acidic endosomes and then reduced to Fe 2+ by the enzyme prostate 3 metal reductase (STEAP 3) (71)

The potential of the wsGNS were further investigated under the presence of common interfering ions/substances 66

201 This evidence reinforces the role of micropinocytosis as a route for the import of different compounds (proteins), to be used as nutrients or signalling molecules in cancer promotion

Finally, encapsulated in stomach acidresistant DRcaps, it gets where it needs to gointact and ready to work.*