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That's significant, but it's not going to make a 60-year-old look 30

Uremic toxins like quinolinic acid can induce lipid peroxidation, destabilizing the phospholipid bilayer of cell membranes (31), leading to increased membrane permeability, cellular dysfunction, and even apoptosis or necrosis, thereby disrupting cellular integrity

It is understandable, however, that few clinicians would choose to restart a medication highly suspected of DILI so as not to expose their patients to further harm

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