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Difficulty initiating and/or maintaining sleep, as well as sleep that is unrefreshing, are key characteristics of insomnia or sleepwake disorder, which frequently co-exists with daytime discomfort or emotional distress
10.1016/j.rama.2014.12.007 184 MichaR.MichasG.MozaffarianD
Rather than targeting obesity through a single mechanism, this 3-way agonist addresses the complex hormonal and metabolic networks that regulate body weight, treating obesity as the multifaceted metabolic disease it truly is
Follow-up Duration : While trials extend to 72 weeks or longer, the chronic nature of obesity requires decades-long, unavailable safety and efficacy data
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