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This tool evaluates ten essential factors, including the analysis category, sample productivity rate in analysis, analytical methodology, reagent quantities, required devices, simultaneous sample handling capability, preconcentration demand, level of process automation, sample construction method, sample quantity, and the ability to estimate analytes concurrently

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Martnez-Sena et al., 2023)] as in vitro models for hepatic toxicity metabolomic studies, because of their stability