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In a study by Son et al., aspartate aminotransferases were demonstrated to be vital in maintaining redox homeostasis in pancreatic ductal adenocarcinoma (PDAC) cells

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Once in circulation, LPS primarily activates the MyD88/TRIF signaling pathways via the LBPCD14MD-2TLR4 complex, inducing the release of pro-inflammatory cytokines facilitated by NF-B and IRF3

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