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doi: 10.1016/j.autrev.2025.103752 69 JiangHZhangXWuYZhangBWeiJLiJet al

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The GSH deficit correlates with oligodendrocyte- and myelin-associated protein depletion caused by a decreased proliferation of oligodendrocyte progenitor cells via Fyn kinase upregulation

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While melanin serves a protective role by absorbing harmful UV radiation, factors like sun exposure, hormonal changes, and genetics can lead to excessive melanin production, resulting in hyperpigmentation and an uneven skin tone

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6 The mechanistic story is a self-reinforcing loop

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