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- Natural Arbutin: Botanical melanin inhibitor - Derived from bearberry leaves and other natural plant sources, Natural Arbutin is a gentle yet highly effective tyrosinase inhibitor that targets melanin production directly at the cellular level, fades existing dark spots and hyperpigmentation, prevents new dark spot formation, and provides botanical brightening that is gentler on skin compared to synthetic alternatives while maintaining excellent efficacy

The ratio of GSH to GSSG is an indicator of oxidative stress

The compound was first characterised and studied by Predrag Sikiri and colleagues at the University of Zagreb beginning in the 1990s