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AstraZeneca said the Phase 1 data so far show a differentiating clinical profile with good tolerability and encouraging glucose and body weight reduction across the dose levels tested compared to placebo. The company had its own GLP-1 agonist in Phase 1 testing for diabetes, but discontinued it earlier this year as part of a strategic portfolio prioritization. It has another in testing for non-alcoholic steatohepatitis.

It could be a neurologist, an internist, anyone who has an area of expertise in the POTS field is going to be probably more helpful than any random cardiologist

During surgery, your surgeon wraps the upper part of the stomach (called the fundus) around the lower part of the oesophagus

It could also increase clarity and concentration, thereby increasing focus