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Activated TBK1 phosphorylates the C-terminal tail (CTT) of STING at several residues including Ser366, which is part of a highly conserved motif (pLXIS) (143, 144)

The following dosage recommendations apply, unless otherwise prescribed: At the beginning of treatment, 1 vial of VITAMIN B12 DEPOT-ROTEXMEDICA (equivalent to 1000 g hydroxocobalamin acetate) is administered twice a week for the first few weeks after diagnosis

[13] There have also been rare reports of high-dose vitamin B (as in injectable form) precipitating skin outbreaks such as acne or rosacea in susceptible persons