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Additional small case series have appeared since

Research published in 2011 found that elderly subjects had markedly lower glutathione concentrations compared to younger adults, with 83% higher fractional synthesis rates in young people

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Methods - Plasma reduced and oxidised glutathione and red blood cells enzymes including acid phosphatase, methemoglobin reductase and transmembrane reductase were evaluated in Portuguese children with Down syndrome and their siblings, who were used as a control group