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The study one of seven trials planned found orforglipron is just as safe as other GLP-1 drugs, with the similar side effects like diarrhea and nausea

Structure raised $748 million in financing in 2025 to fund the aleniglipron programme and its broader oral metabolic portfolio

But it is changing unevenly, and without deliberate policy intervention, the GLP-1 revolution risks becoming one of the starkest examples in modern medicine of a breakthrough that transformed outcomes for those who could afford it, and passed everyone else by.

Putting GLP-1 RAs and Thyroid Cancer in Context: Additional Evidence and Remaining Doubts