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The measurements were based on the reaction between MDA and thiobarbituric acid (TBA)

The standard protocol escalates doses slowly for exactly this reason, to give the body time to adapt before increasing stimulation further

This means, in our hypothetical example, Kaiser wouldbefore factoring in the cost of the drugsave over $11 billion ($1,900 times 6.048 million = 11.49 billion) in the first year if it could give one of the modern weight loss drugs to all its members with obesity