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Constituents such as polyphenols, flavonoids, alkaloids, terpenes, saponins, and tannins have positively affected kidney health and various phytochemicals that exhibit anti-renal fibrosis effects through multiple signaling pathways [236, 237]

Over the maximum follow-up of ~30 years, there were 7069 events (1937 ASCVD, 2109 heart failure, 3288 CKD and 4785 deaths)