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King MK, Pardo M, Cheng Y, Downey K, Jope RS, Beurel E

Li XL, Zhou J, Chen ZR, Chng WJ

When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)

1 These are benign neoplasms of melanocytic nevus cells that begin at intradermal-epidermal junction (junctional nevus), and over time tend to migrate into the dermis while a component remains in contact with the basal layer (compound nevus)