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However, when these systems falter, the consequences are profound: misfolded proteins accumulate, aberrant antigen presentation fuels immune hyperactivation, and chronic inflammation spirals out of control

2014;129(25 Suppl 2):S102S138

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Promoting Adherence to Clinical Guidelines: PA criteria are based on evidence-based guidelines, encouraging healthcare providers to follow best practices in prescribing, which leads to improved patient outcomes and standardized care