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Edkins in the discovery of gastrin' World Journal of Surgery , 21, 226-34

Refrigerated storage is necessary to preserve blood until needed for transfusion therapies, but it leads to the progressive accumulation of biochemical and morphological alterations, mainly triggered by oxidative stress to proteins and lipids, a phenomenon known as the storage lesion 9

Therefore, studying the mutual interference between cancer cell metabolism reprogramming and CTLs, as well as clarifying the roles of relevant nutrients and their metabolites in the anti-tumor immune process, may improve the therapeutic effects of existing treatment methods and reveal new potential therapeutic targets for further research

American academy of otolaryngology-head and neck surgery, 27, 30 American clinical guidelines, 25, 27, 30, 38