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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

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Insert image: Combination therapy protocols and compatibility chart

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[12] For larger lesions or those with a more aggressive histology, adjuvant radiation is recommended

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Some provide ongoing monitoring while others refer back to your primary care physician

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