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Coenzyme Q10 serves to couple mitochondrial oxidative phosphorylation and fatty acid B-oxidation, and attenuates nlrp3 inflammasome activation

Archiv Psychiatr Nervenkrankheit 1944;117:76-136

Eventually, cell mitophagy occurs, and autophagy is detected in blood mononuclear cells and plasma from patients with fibromyalgia [14]

Additionally, homotaurine reduced the increase in oxidative stress biomarkers and inflammatory cytokines, such as IL-1, IL-6, and TNF- levels, caused by VPA in rats, decreased pyknosis in the prefrontal cortex, and restored the size and number of Purkinje cells in the cerebellum and regulated the dysregulated expression of GAD67 due to VPA exposure (158)