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Integrate new knowledge of overweight/obesity and GLP-1 therapy into practice

Patients report subjective energy improvements within the first week (attributed to B12 and improved mitochondrial function), but fat oxidation measurable on a scale typically begins in week 34

Instead of judging progress by the scale alone, clinicians may also track waist measurements, blood pressure, glucose markers, energy level, strength, and how clothing fits

Short-form tips that anyone on GLP-1 agonists should follow include: Eat smaller, more frequent meals, aligning with the GLP-1s metabolic effects and maintaining energy levels