when to switch from semaglutide to tirzepatide Transitioning Treatments: What Expect Changing Switching from Semaglutide to Tirzepatide:

Cohorts were matched for current age, age at index event, sex, race, ethnicity, and multiple comorbidities including chronic obstructive pulmonary disease, asthma, diabetic gastroparesis, chronic bronchitis, gastroesophageal reflux disease, chronic rhinitis, postnasal drip, heart failure, tobacco use, overweight status, obesity status, metformin use, insulin use, and angiotensin-converting enzyme inhibitor use

Li M, Smith CJ, Walker MT,Smith TJ

This makes sense given that GLP-1 has multiple effects on our biochemistries that culminate in the reduction of circulating glucose levels

The primary role of astrocytes is to provide metabolic support to neurons under both physiological and pathological conditions