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Description

PHB2 is a multifunctional protein located in the inner mitochondrial membrane that binds to LC3 and triggers mitophagy, and when PHB2 is absent it causes a selective deletion of the long isoform of OPA1, which leads to abnormal mitochondrial cristae morphology and fragmentation [82, 90]

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Promotes a leaner, more defined look

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Safety: Both medicines can cause gastrointestinal side effects and need clinical review

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Coverage is targeted rather than universal, focusing on those with the greatest potential health benefit

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