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Carnitine, Acylcarnitines and Fatty Acid Transport into Mitochondria The substrates for oxidation and most of the energy production in cells are unesterified fatty acids, which originate from three main sources: exogenous fatty acids that enter cells from the circulation, either from the diet or by mobilization from other tissues, those that arise via synthesis de novo from acetyl-CoA, and those released within the cell by the hydrolysis of phospholipids and triacylglycerols

Growth hormone treatment and risk of malignancy

Therefore, carnitine/acylcarnitine not only play roles in muscle energy metabolism but also participate in the whole-body energy balance and fatigue perception by affecting neuromuscular signaling, underscoring the potential importance of carnitine in exercise physiology, exercise recovery and performance improvement

Some people may experience mild side effects such as heartburn and indigestion