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National Poison Center Trends in GLP-1 Receptor Agonist Exposures Following FDA Approval for Weight Loss
In clinical trials of semaglutide injection for weight management, patients treated with semaglutide had a mean increase from baseline in amylase of 16% and lipase of 39%
However, starting in late 2023, the FDA changed its enforcement stance and restricted many commonly used peptides, including BPC-157 and TB-500
Contact your healthcare provider immediately if you experience: Severe, persistent abdominal pain (could indicate pancreatitis, gallbladder disease, or surgical complications) Persistent vomiting preventing fluid intake (risk of dehydration and acute kidney injury) Signs of dehydration (dark urine, dizziness, reduced urination) Symptoms of hypoglycaemia if taking other diabetes medications Unusual fatigue, fever, or wound-related concerns The Ozempic SmPC specifically mentions pancreatitis and gallbladder disease as potential risks that require prompt medical attention
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