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Beyond weight loss, retatrutide showed improvements in various cardiometabolic measures

Acknowledgments The authors are grateful to Claudia Jonak (Vienna, Austria) for kindly providing seeds of the g6pd5-1 g6pd6-2 double mutant, and thank Paulina Heinkow for sample preparation and technical assistance within the MS Proteomics Unit Biology of Plants of the University of Mnster

These existing options are disulfiram, acamprosate, and naltrexone

Additional safety considerations include the risk of dehydration and acute kidney injury from gastrointestinal side effects, hypersensitivity reactions including anaphylaxis, and injection-site reactions