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Its a paper that has become a North Star for Sikirics work, and he invoked it now to defend his project: The passage does not mention receptors, Sikiric pointed out, suggesting to him that Robert didnt view them as essential for cytoprotection

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The FDA has made clear that this labeling doesn't exempt products from drug regulations when they're clearly intended for human use

28 However, there are no GLP-1 receptors in the eye so it is most likely that any worsening of retinopathy is related to the rapid fall in glucose levels with these agents