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For the last-month rule, the testing period begins with the last month of your tax year and ends on the last day of the 12th month following that month (for example, December 1, 2019, through December 31, 2020)

This is not a pharmacokinetic effect but rather a physiological one

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Wegovy, the only form of semaglutide approved for weight loss, is intended for use by those with either of the following: a BMI of 27 or greater and one weight-related health condition, such as high blood pressure a BMI of 30 or greater Both Ozempic and Rybelsus are intended for use in people with type 2 diabetes