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El cortisol elevado por estrs prolongado y la privacin de sueo pueden promover resistencia a la insulina y dificultar la prdida de peso, incluso con tratamiento farmacolgico adecuado

Importantly, GLP-1 only triggers insulin when blood sugar is high, which reduces the risk of hypoglycemia (dangerously low blood sugar)

The Department of Health and Social Care (DHSC) has warned that the shortage of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) will continue, with supply not expected to return to normal until at least the end of 2024

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