Catecholamine Catabolism The catecholamine, DOPA, dopamine, epinephrine, and norepinephrine are catabolized to inactive compounds through the sequential actions of enzymes that include catecholamine- O -methyltransferase (COMT) and monoamine oxidase (MAO)
Park H, DiNatale D, Chung M, Park Y, Lee J, Koo S, Park HJ, DiNatale DA, Chung M-Y, Park Y-K, Lee J-Y, Koo SI, OConnor M, Manautou JE, Bruno RS, Bruno R (2011) Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice
However, because it improves insulin sensitivity, diabetes medications may need to be adjusted
Solutions and Innovations Development of Oral Formulations: Companies like Eli Lilly are focusing on oral GLP-1 drugs to improve patient adherence and convenience