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In hepatocellular carcinoma (HCC), LCACs are effectively loaded into the mitochondria of lymphocytes, resulting in the inhibition of invariant natural killer T (iNKT) cell expansion and the promotion of their senescence while simultaneously facilitating tumor evasion of immune surveillance [66]

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Jger K, Garreis F, Posa A et al (2010) Functional relationship between cationic amino acid transporters and -defensins: Implications for dry skin diseases and the dry eye