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The inhibitor action of GLP-1 on glucagon levels is often over-looked in favor of its role as an insulin secretagogue, but it is clear that pharmacologically this is one mechanism by which GLP-1r agonists improve glycemia in T2DM patients (86)

While MBS has high upfront costs, long-term cost savings from reduced chronic disease burden make it consistently cost-effective or even cost-saving in many studies

The TGA has warned advertising or promoting unapproved peptides was likely to breach Australian therapeutic goods advertising laws

It is thought to arise from a combination of microvascular dysfunction, chronic inflammation, and increased interstitial pressure that may compress peripheral nerves