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To further investigate the impact of inhibiting OA uptake on reducing the formation of CD8 + Tsen and its resulted effect on anti-tumor immunity, we assessed the proliferative capacity of CD8 + T cells using CCK8 and Ki67 staining, measured the expression levels of effector molecules (GZMB, FasL, and IFN-) using RT-PCR and flow cytometry, as well as the expression levels of key SASP (senescence-associated secretory phenotype) factors such as IL-6 and inhibitory cytokines like IL-10 in CD8 + T cells using flow cytometry

One 10 mg vial contains 5 mg of each

Zepbound is an FDA-approved finished drug manufactured by Eli Lilly

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