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Conclusion: These findings indicate sex-specific effects of PFOA exposure on liver and whole-body lipid homeostasis, mediated in part via PPAR dependent mechanisms with important differences between mouse and human PPAR, and identifies hPPARa mice as a valuable in vivo model for toxicological research

Reduced glutathione does not further reduce contrast-induced nephropathy in elderly patients with diabetes receiving percutaneous coronary intervention

Treatment of HepG2 cells with different concentrations of NFT or DEM for 24 h led to a concentration-dependent increase in Nrf2 and GCLC protein levels, whereas no significant change was observed in the levels of the modifier subunit, GCLM (Fig

Downtime: Minimal to no