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Although many AAS users believe that PEDs are safe for long-term use, the vast majority would stop using AAS if they experience a serious health problem (Bonnecaze et al., 2020)

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Another reaction that generates free radicals is the purine metabolism, where xanthine oxidase catalyses the conversion of hypoxanthine to xanthine and subsequently to uric acid, and during its re-oxidation, molecular oxygen is reduced to superoxide [31]