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Future success will depend not only on refining therapeutic targets but also on optimizing dosing strategies and establishing reliable, non-invasive biomarkers for senescence, enabling safe, effective, and personalized application in clinical aging medicine

Following the finding that the cancer cell lines did not elevate telomerase enzyme activity upon epitalon treatment but did elongate telomeres, we investigated the other commonly used mechanism to extend telomeres in mammals, ALT (Alternative Lengthening of Telomeres)

Glutathione GSH concentration in blood increased after absorption from the orobuccal mucosa, the change being statistically significant compared to basal levels

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