When melanocytes (melanin-producing cells) become hyperactive, they create patches of darker skin that can be difficult to fade with topical treatments alone
It consists of six Traditional Chinese medicine (TCM) herbs, of which Saccharum granorum (Yitang, YT) is its principal drug, Cinnamomum cassia Presl (Guizhi, GZ) and Paeonia lactiflora Pall (Baishao, BS) are its assistant drugs, and Ziziphus jujuba Mill (Dazao, DZ), Zingiber officinale Rosc (Shengjiang, SJ) and Glycyrrhiza uralensis Fisch (Gancao, GC) are its complement drugs. Studies have shown that XJZ has a good effect on the treatment of CAG by regulating intestinal microbiota and bile acid metabolism [6], but its mechanism of action remains to be studied
Key Takeaways GHK-Cu is a naturally occurring copper peptide that may have potentially beneficial effects in supporting skin firmness, hair growth appearance, and collagen production AHK-Cu is a synthetic copper peptide that has shown positive effects on hair and scalp health appearance in available research The comparison between AHK-Cu vs GHK-Cu shows GHK-Cu has the broader research base for both skin appearance and hair growth with consistent application Some users may explore AHK-Cu and GHK-Cu together, however, published research on the efficacy of this approach is limited PLU Laboratories offers both GHK-Cu and AHK-Cu peptide serums, with GHK-Cu as our flagship for skin and hair support and AHK-Cu available as a dedicated hair-focused option What is GHK-Cu
ERS activates the protein kinase R (PKR)-like endoplasmic reticulum (ER) kinase (PERK)/eukaryotic translation initiation factor 2 (eIF2)/activating transcription factor 4 (ATF4) pathway, upregulating the pro-apoptotic protein C/EBP homology protein (CHOP), suppressing Bcl-2 expression, and activating Caspase-12 (replaced by Caspase-4 in humans)a pro-apoptotic branch of the unfolded protein response (UPR) [15]
