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This is demonstrated by a decreased ability to opsonize bacteria-derived polysaccharides in vitro after vaccination [373]

While the results from studies using native OXM in rodents and humans were promising, the short half-life in vivo and the large amount of peptide required to produce an effect made it a poor choice as a treatment in humans

[DOI] [PMC free article] [PubMed] [Google Scholar] 265.Niehues P., Wegner F.K., Wolfes J., Willy K., Ellermann C., Vollenberg R., Reinecke H., Rosenow F., Lepper J., Sackarnd J., et al