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Protection was antigen-dependent, as irrelevant antigen with immunomodulators in LNPs was ineffective, similar to buffer control

Chem Res Toxicol 16:295303 Coen M, Ruepp SU, Lindon JC, Nicholson JK, Pognan F, Lenz EM, Wilson ID (2004) Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

This pathway had been available under the previous TGA system but was not utilised by industry due to the requirement for multiple unredacted NRA reports, which were difficult to obtain

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