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Koenig and Preston Sutton analyzed Raman spectra of poly-L-lysine in both aqueous solution and solid state, and showed that although this homopolymer behaves as a random coil in aqueous solutions, it folds into -helical structure in solid state (Koenig and Sutton, 1970)

In accordance with NICE guidance , management of restless legs syndrome involves identifying and treating underlying causes, addressing lifestyle factors, and considering specific treatments if symptoms are moderate to severe and significantly impact quality of life

Most patients notice appetite suppression within the first 1 to 2 weeks

PMID 11923464