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Reconstitution supplies are also important to consider

Note: Improved bioavailability means you can achieve your wellness goals with smaller, more intentional doses, which reduces the burden on your digestive system

A more recent hypothesis postulates that high-dose folic acid redirects the active form of vitamin B12 in serum, i.e., holotranscobalamin, either toward the bone marrow to support reticulocyte synthesis that is induced by folic acid in B12-deficient patients, or into the urine in which it is excreted instead of being taken up and recycled into circulation through the kidneys (84)

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